Tranform EHR Data Into Actionable Insights

Advancing EHR data in clinical research—and training the next generation to use it.

The Problem

Real-world data (RWD), such as electronic health records (EHR), hold immense potential to accelerate medical discovery and product development. Yet, technical complexities, prohibitive costs, and a shortage of specialized talents prevent researchers from harnessing its full power.

Collaborative Research Engine

We build a collaborative space where clinical scientists, data scientists, and data providers work together on selected, high-quality research manuscripts initiated from our academic partners.

We foster shared interests and build connections between industry and academia.

We offer hands-on training for college and graduate students, medical fellows, and junior investigators on designing and conducting real-world data studies.

We develop algorithms and tools for EHR data standardization, quality assessment, and analytics.

Industry-Academic Partnership

Future Leadership Fellowship

Methodological Innovation Lab

Our Solutions

Academic Partners

Data Participants

Sponsorship

Our Data

Freely Accessible to Researchers

Active Data Cohort

Autism spectrum disorder cohor: ~200K incident autism patients from 2018 to 2025.
Alzheimer's disease cohort: ~100K incident Alzheimer's disease patients from 2018 to 2025, adult population.
Mild cognitive impairment (MCI) cohort: ~80K incident MCI patients from 2018 to 2025, adult population.
Pancreatic cancer cohort: ~45K incident pancreatic cancer patients from 2019 to 2022, adult population.
Breast cancer cohort: ~70K incident breast cancer female patients from 2020 to 2021, adult population.
Sepsis pediatric cohort: ~30K incident sepsis pediatric patients from 2018 to 2025.

General Data

U.S. national structured EHR data: 120 - 150 million patient lives (sponsored by Truveta)
- Demographics and Vital Statistics
- Encounter (outpatient, inpatient, emergency etc.)
- Condition / Procedure
- Vital Sign and Labs
- Medication Prescription and Dispense
- Immunology
- Geographic and Socioeconomic Information
- Notes and Imaging (not included for free access)
Open claims data linked to EHR

Help us enabling free data access to our researchers

Our Work

For Researchers

We evaluate manuscript proposals from researchers on collaboration and use of our data. We will offer data as well as study design and analytics support.

Submit a Proposal

For Corporate Sponsors

Sponsors can submit research topics, and we will find and match our academic partners to the topics to promoate academia-industry collaboration.

Submit Interests

For Individuals

Individuals such as clinicians and patients are welcome to submit research questions, and we will grow research projects out of them.

Submit a Research Question

EHR Data Quality Framework

There are concerns about the reliability and the quality of EHR data for use in clinical research To address this challenge, we propose a quantitative, score-based QA framework for categorical and continuous EHR data. We will present demo results for sex and weight in this poster

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Volunteering

Past and Ongoing Projects

Liver metastasis Mechanism in breast cancer

Tumor-derived FXII engages the intrinsic coagulation cascade to support breast cancer liver metastasis

Completed

Anti-Psychosis Drug Effect on Mortality of Alzheimer's Disease

The development of Alzheimer can be fatal as senior patients are susceptible to other comorbidities. Anti-psychosis drugs are sometimes used to treat AD as a way to help improve cognition. We studied how use of anti-psychosis drugs impacts mortality of patients with Alzheimer's disease.

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